TRIM74

Across TCGA cell cohorts, TRIM74 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,789 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TRIM74-associated GO terms across cancer lineages are Sperm motility, Cilium or flagellum-dependent cell motility, and Flagellated sperm motility. Each is linked with TRIM74 in more than 11 cancer types. Because this analysis shows association rather than direction, both TRIM74-to-partner and partner-to-TRIM74 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sperm motility grouped by TRIM74-low versus TRIM74-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM74→partner) and Y-score (partner→TRIM74) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Sperm motility →	-0.102	-0.824	<.001	.004	3	12
KIDNEY	Cilium or flagellum-dependent cell motility →	-0.090	-0.652	<.001	.003	3	12
KIDNEY	Flagellated sperm motility →	-0.102	-0.824	<.001	.004	3	12
KIDNEY	Cilium-dependent cell motility →	-0.090	-0.652	<.001	.003	3	12
KIDNEY	Cilium movement involved in cell motility →	-0.096	-0.617	<.001	.005	3	12
OESOPHAGUS	Negative regulation of autophagy →	+0.070	+0.606	.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,789 associations by consensus.

Sperm motility by TRIM74 expression — KIDNEY

Explore this box plot interactively →