TRIM74

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TRIM74 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM74-associated genes across cancer lineages are OR1M1. Each is linked with TRIM74 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM74-to-partner and partner-to-TRIM74 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1M1 grouped by TRIM74-low versus TRIM74-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM74→partner) and Y-score (partner→TRIM74) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaOR1M1 →+0.036+5.969<.001.00131
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OR1M1 by TRIM74 expression — BLOOD_Leukemia

Box plot of OR1M1 in TRIM74-low vs TRIM74-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration