TRIM68

Across TCGA cell cohorts, TRIM68 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,023 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM68-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and Macroautophagy. Each is linked with TRIM68 in more than 13 cancer types. Because this analysis shows association rather than direction, both TRIM68-to-partner and partner-to-TRIM68 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Process utilizing autophagic mechanism grouped by TRIM68-low versus TRIM68-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM68→partner) and Y-score (partner→TRIM68) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Process utilizing autophagic mechanism →	+0.056	+0.717	<.001	.001	3	14
KIDNEY	Autophagy →	+0.056	+0.717	<.001	.001	3	14
KIDNEY	Macroautophagy →	+0.055	+0.717	<.001	.001	3	13
BLOOD_Leukemia	Telomere tethering at nuclear periphery →	+0.129	+0.525	<.001	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cilium assembly →	+0.071	+1.101	<.001	<.001	3	13
LIVER	Negative regulation of organelle assembly →	+0.077	+1.278	<.001	.004	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,023 associations by consensus.

Process utilizing autophagic mechanism by TRIM68 expression — KIDNEY

Explore this box plot interactively →