TRIM67

Across TCGA cell cohorts, TRIM67 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,791 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM67-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, ATP metabolic process, and Negative regulation of endoplasmic reticulum unfolded protein response. Each is linked with TRIM67 in more than 7 cancer types. Because this analysis shows association rather than direction, both TRIM67-to-partner and partner-to-TRIM67 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by TRIM67-low versus TRIM67-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM67→partner) and Y-score (partner→TRIM67) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of syncytium formation by plasma membrane fusion →	+0.093	+0.030	<.001	<.001	3	8
SKIN	ATP metabolic process →	+0.070	+0.334	<.001	.006	3	7
BLOOD_Leukemia	Negative regulation of endoplasmic reticulum unfolded protein response →	+0.087	+0.209	<.001	.001	3	7
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.101	+0.035	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Lysosomal lumen acidification →	+0.072	+0.127	<.001	.005	3	7
BLOOD_Lymphoma	Vesicle coating →	+0.059	+0.026	.002	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,791 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by TRIM67 expression — BLOOD_Lymphoma

Explore this box plot interactively →