TRIM65

Across TCGA cell cohorts, TRIM65 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible TRIM65-associated genes across cancer lineages are DBX1, CA5A, and C16orf90. Each is linked with TRIM65 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM65-to-partner and partner-to-TRIM65 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DBX1 grouped by TRIM65-low versus TRIM65-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM65→partner) and Y-score (partner→TRIM65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	DBX1 →	+0.006	+5.087	<.001	.004	3	1
URINARY_TRACT	CA5A →	+0.020	+5.087	<.001	.004	3	1
URINARY_TRACT	C16orf90 →	+0.023	+5.087	<.001	.004	3	1
LARGE_INTESTINE	ELOA3DP →	+0.036	+4.273	<.001	.006	3	1
CNS	CCL1 →	+0.412	+4.887	<.001	<.001	3	1
CNS	RHO →	+0.022	+4.247	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

DBX1 by TRIM65 expression — URINARY_TRACT

Explore this box plot interactively →