TRIM62

Across TCGA cell cohorts, TRIM62 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,787 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM62-associated GO terms across cancer lineages are Negative regulation of RNA splicing, Negative regulation of mRNA processing, and Positive regulation of organelle assembly. Each is linked with TRIM62 in more than 11 cancer types. Because this analysis shows association rather than direction, both TRIM62-to-partner and partner-to-TRIM62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA splicing grouped by TRIM62-low versus TRIM62-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM62→partner) and Y-score (partner→TRIM62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of RNA splicing →	+0.089	+0.869	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mRNA processing →	+0.096	+0.572	<.001	<.001	3	12
SOFT_TISSUE	Positive regulation of organelle assembly →	+0.072	+1.285	<.001	<.001	3	12
SKIN	Positive regulation of antifungal innate immune response →	+1.372	+1.430	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.061	+0.570	.002	.001	3	11
LUNG_NSCLC_LUSC	Regulation of organelle assembly →	+0.062	+0.794	.003	.006	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,787 associations by consensus.

Negative regulation of RNA splicing by TRIM62 expression — OVARY

Explore this box plot interactively →