TRIM62

Across TCGA cell cohorts, TRIM62 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRIM62-associated genes across cancer lineages are SLC38A8, LMX1A, and OR52B2. Each is linked with TRIM62 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM62-to-partner and partner-to-TRIM62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC38A8 grouped by TRIM62-low versus TRIM62-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM62→partner) and Y-score (partner→TRIM62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SLC38A8 →	+0.099	+4.191	<.001	.007	3	2
BLOOD_Lymphoma	LMX1A →	+0.042	+4.714	<.001	.002	3	1
BLOOD_Lymphoma	OR52B2 →	+0.021	+4.714	.006	.002	3	1
LARGE_INTESTINE	AHSA1 →	+0.556	+3.064	<.001	.009	3	1
LARGE_INTESTINE	ALDH6A1 →	+1.178	+3.064	<.001	.009	3	1
LARGE_INTESTINE	GNMT →	+0.314	+3.302	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

SLC38A8 by TRIM62 expression — BLOOD_Lymphoma

Explore this box plot interactively →