TRIM56

Across TCGA pan-cancer cohorts, TRIM56 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TRIM56 data layer compared with 20 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TRIM56 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TRIM56 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LUAD, HNSC, and LSCC are the cancer types where TRIM56 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	II,III,IV	0.971	0.702	.001	29	view →
HNSC	OS	Quartile	All	0.600	0.829	.013	7	view →
LSCC	DFS	Tertile	All	0.584	0.808	.031	5	view →
UCEC	OS	Tertile	III,IV	0.484	1.000	.049	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TRIM56–LUAD (DFS)

Open the LUAD breakdown →