TRIM55

Across TCGA cell cohorts, TRIM55 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,497 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TRIM55-associated GO terms across cancer lineages are CD4-positive, alpha-beta T cell differentiation, Positive regulation of canonical NF-kappaB signal transduction, and Oncogene-induced cell senescence. Each is linked with TRIM55 in more than 5 cancer types. Because this analysis shows association rather than direction, both TRIM55-to-partner and partner-to-TRIM55 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4-positive, alpha-beta T cell differentiation grouped by TRIM55-low versus TRIM55-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM55→partner) and Y-score (partner→TRIM55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	CD4-positive, alpha-beta T cell differentiation →	+0.103	+2.997	.001	<.001	3	6
LUNG_NSCLC_LUAD	Positive regulation of canonical NF-kappaB signal transduction →	+0.050	+1.296	<.001	.001	3	5
CNS	Oncogene-induced cell senescence →	+0.159	+0.988	<.001	.003	3	5
LUNG_NSCLC_LUAD	Inflammatory response to wounding →	+0.144	+1.132	.003	.008	2	6
SOFT_TISSUE	L-glutamate biosynthetic process →	+0.123	+3.103	.006	.001	3	5
UPPER_AERODIGESTIVE_TRACT	Leukocyte apoptotic process →	+0.076	+0.797	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,497 associations by consensus.

CD4-positive, alpha-beta T cell differentiation by TRIM55 expression — KIDNEY

Explore this box plot interactively →