TRIM53CP

Across TCGA pan-cancer cohorts, TRIM53CP RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated TRIM53CP data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher TRIM53CP RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TRIM53CP expression acts as an unfavorable survival marker, although some lineages such as MESO show a favorable association.

ACC, HNSC, and PAAD are the cancer types where TRIM53CP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.269	0.846	<.001	84	view →
HNSC	OS	Tertile	II,III,IV	0.365	0.652	<.001	72	view →
PAAD	OS	Tertile	All	0.087	0.640	<.001	45	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	36	view →
UVM	DFS	Tertile	All	0.221	0.618	.042	18	view →
MESO	DFS	Tertile	All	0.448	0.186	.025	15	view →
BLCA	DFS	Tertile	III,IV	0.214	0.500	.022	9	view →
LGG	DFS	Tertile	All	0.624	0.749	.034	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

TRIM53CP–ACC (OS)

Open the ACC breakdown →