TRIM50

Across TCGA patient cohorts, TRIM50 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,604 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRIM50-associated proteins across cancer lineages are BZW1, COL17A1_S174, and SVIL_S547. Each is linked with TRIM50 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRIM50-to-partner and partner-to-TRIM50 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM50 versus BZW1 in PDAC, with a Pearson correlation of -0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM50→partner) and Y-score (partner→TRIM50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	BZW1 →	-0.420	-0.700	<.001	<.001	3	3
LUAD	COL17A1_S174 →	-1.501	-0.315	.005	.007	3	3
GBM	SVIL_S547 →	+0.634	+0.161	.001	.002	3	3
PDAC	LIG4 →	+0.288	+0.506	<.001	.006	3	3
GBM	GIMAP8 →	+0.384	+0.177	.002	<.001	3	3
PDAC	MICALL2_S649 →	-0.565	-0.604	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,604 associations by consensus.

TRIM50 vs BZW1 — PDAC

Explore this scatter interactively →