TRIM49B

Across TCGA patient cohorts, TRIM49B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,689 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TRIM49B-associated GO terms across cancer lineages are Skeletal system morphogenesis, Negative regulation of Wnt signaling pathway, and Respiratory system development. Each is linked with TRIM49B in more than 8 cancer types. Because this analysis shows association rather than direction, both TRIM49B-to-partner and partner-to-TRIM49B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Skeletal system morphogenesis grouped by TRIM49B-low versus TRIM49B-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM49B→partner) and Y-score (partner→TRIM49B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Skeletal system morphogenesis →	+0.054	+0.108	<.001	<.001	3	9
STAD	Negative regulation of Wnt signaling pathway →	+0.056	+0.098	<.001	<.001	3	9
STAD	Respiratory system development →	+0.059	+0.097	<.001	<.001	3	9
STAD	Negative regulation of protein localization →	+0.072	+0.099	<.001	<.001	3	8
STAD	Regulation of extrinsic apoptotic signaling pathway in absence of ligand →	+0.051	+0.103	<.001	<.001	3	8
STAD	Regulation of smoothened signaling pathway →	+0.048	+0.070	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,689 associations by consensus.

Skeletal system morphogenesis by TRIM49B expression — STAD

Explore this box plot interactively →