TRIM49B

Across TCGA cell cohorts, TRIM49B RNA expression is significantly associated with the mutation status of many other genes, with 257 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM49B-associated genes across cancer lineages are DCC, PCNT, and LILRB2. Each is linked with TRIM49B in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM49B-to-partner and partner-to-TRIM49B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCC grouped by TRIM49B-low versus TRIM49B-high in PANCREAS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM49B→partner) and Y-score (partner→TRIM49B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DCC →	+4.029	+0.018	.007	<.001	3	2
KIDNEY	PCNT →	+3.491	+0.023	.006	<.001	3	2
BLOOD_Lymphoma	LILRB2 →	+3.714	+0.601	.006	<.001	3	2
STOMACH	NF1 →	+3.794	+0.009	.003	<.001	3	2
UPPER_AERODIGESTIVE_TRACT	HECTD4 →	+4.129	+0.121	.002	.001	3	2
BLOOD_Leukemia	WDR59 →	+2.967	+0.070	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 257 associations by consensus.

DCC by TRIM49B expression — PANCREAS

Explore this box plot interactively →