TRIM49

Across TCGA patient cohorts, TRIM49 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,381 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TRIM49-associated GO terms across cancer lineages are Respiratory chain complex IV assembly, Protein-DNA complex assembly, and Protein localization to mitochondrion. Each is linked with TRIM49 in more than 7 cancer types. Because this analysis shows association rather than direction, both TRIM49-to-partner and partner-to-TRIM49 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Respiratory chain complex IV assembly grouped by TRIM49-low versus TRIM49-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM49→partner) and Y-score (partner→TRIM49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Respiratory chain complex IV assembly →	+0.087	+0.030	<.001	<.001	3	8
STAD	Protein-DNA complex assembly →	+0.081	+0.043	<.001	<.001	3	8
STAD	Protein localization to mitochondrion →	+0.092	+0.039	<.001	<.001	3	8
STAD	Exit from mitosis →	+0.083	+0.034	<.001	<.001	3	8
STAD	rRNA metabolic process →	+0.105	+0.041	<.001	<.001	3	8
STAD	Morphogenesis of a polarized epithelium →	+0.069	+0.033	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,381 associations by consensus.

Respiratory chain complex IV assembly by TRIM49 expression — STAD

Explore this box plot interactively →