TRIM48

Across TCGA patient cohorts, TRIM48 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,325 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TRIM48-associated GO terms across cancer lineages are 5-phosphoribose 1-diphosphate metabolic process, Monosaccharide biosynthetic process, and Mitochondrial gene expression. Each is linked with TRIM48 in more than 5 cancer types. Because this analysis shows association rather than direction, both TRIM48-to-partner and partner-to-TRIM48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 5-phosphoribose 1-diphosphate metabolic process grouped by TRIM48-low versus TRIM48-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM48→partner) and Y-score (partner→TRIM48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	5-phosphoribose 1-diphosphate metabolic process →	+0.077	+0.127	<.001	.005	3	6
STAD	Monosaccharide biosynthetic process →	+0.071	+0.112	<.001	<.001	3	6
STAD	Mitochondrial gene expression →	+0.108	+0.100	<.001	.001	3	5
STAD	Nucleoside triphosphate biosynthetic process →	+0.098	+0.093	<.001	<.001	3	5
STAD	Ribonucleoside monophosphate biosynthetic process →	+0.090	+0.091	<.001	.002	3	5
STAD	Telomerase RNA localization →	+0.095	+0.184	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,325 associations by consensus.

5-phosphoribose 1-diphosphate metabolic process by TRIM48 expression — STAD

Explore this box plot interactively →