TRIM46

Across TCGA cell cohorts, TRIM46 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,725 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM46-associated GO terms across cancer lineages are Cell division, Regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with TRIM46 in more than 11 cancer types. Because this analysis shows association rather than direction, both TRIM46-to-partner and partner-to-TRIM46 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell division grouped by TRIM46-low versus TRIM46-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM46→partner) and Y-score (partner→TRIM46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cell division →	+0.065	+1.251	<.001	.002	3	12
OESOPHAGUS	Regulation of myoblast fusion →	+0.108	+1.040	.007	.004	3	12
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.129	+1.050	.003	.002	3	12
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.137	+1.400	.009	.001	3	11
OESOPHAGUS	Nucleoside triphosphate biosynthetic process →	+0.105	+1.221	.002	<.001	2	12
OESOPHAGUS	Ribonucleoside triphosphate biosynthetic process →	+0.104	+1.103	.004	.002	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,725 associations by consensus.

Cell division by TRIM46 expression — LUNG_SCLC

Explore this box plot interactively →