TRIM45

Across TCGA patient cohorts, TRIM45 protein abundance is significantly associated with the RNA expression of many other genes, with 1,916 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRIM45-associated genes across cancer lineages are GALNT16, PRPS2, and SYTL4. Each is linked with TRIM45 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM45-to-partner and partner-to-TRIM45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM45 versus GALNT16 in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM45→partner) and Y-score (partner→TRIM45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GALNT16 →	+1.646	+0.676	<.001	.001	3	1
BRCA	PRPS2 →	-1.035	-1.013	.005	.005	3	1
BRCA	SYTL4 →	+1.317	+0.802	.001	.008	3	1
BRCA	NUTF2 →	-0.556	-0.559	.007	.004	3	1
BRCA	PITRM1 →	-0.638	-0.681	<.001	.002	3	1
BRCA	DCPS →	-0.636	-0.627	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,916 associations by consensus.

TRIM45 vs GALNT16 — BRCA

Explore this scatter interactively →