Across TCGA patient cohorts, TRIM39-RPP21 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,262 significant associations in total. THCA shows the largest number of these associations.

The most reproducible TRIM39-RPP21-associated GO terms across cancer lineages are G2/MI transition of meiotic cell cycle, Mitotic DNA replication, and Spliceosomal conformational changes to generate catalytic conformation. Each is linked with TRIM39-RPP21 in more than 11 cancer types. Because this analysis shows association rather than direction, both TRIM39-RPP21-to-partner and partner-to-TRIM39-RPP21 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM39-RPP21→partner) and Y-score (partner→TRIM39-RPP21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	G2/MI transition of meiotic cell cycle →	+0.102	+0.079	<.001	<.001	3	12
LUSC	Mitotic DNA replication →	+0.030	+0.045	<.001	<.001	3	10
READ	Spliceosomal conformational changes to generate catalytic conformation →	+0.039	+0.039	<.001	<.001	3	9
ACC	Nuclear pore localization →	+0.055	+0.073	.004	<.001	2	9
TGCT	DNA replication initiation →	+0.054	+0.098	<.001	.001	3	8
TGCT	Obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' →	+0.035	+0.082	.001	.008	1	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,262 associations by consensus.

Exploration

TRIM39-RPP21 survival (RNA) · tumor vs normal (RNA) · all TRIM39-RPP21 data types