TRIM37

Across TCGA pan-cancer cohorts, TRIM37 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TRIM37 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TRIM37 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TRIM37 expression acts as an unfavorable survival marker, although some lineages such as UCEC and GBM show a favorable association.

UCEC, PDAC, and GBM are the cancer types where TRIM37 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	1.000	0.386	.003	34	view →
PDAC	DFS	Median	III,IV	0.189	0.928	<.001	23	view →
GBM	DFS	Quartile	All	0.930	0.590	.001	15	view →
LSCC	OS	Median	III,IV	0.871	0.501	.015	8	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TRIM37–UCEC (DFS)

Open the UCEC breakdown →