TRIM37

Across TCGA cell cohorts, TRIM37 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,264 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM37-associated GO terms across cancer lineages are Aggresome assembly, Negative regulation of beige fat cell differentiation, and Negative regulation of centriole replication. Each is linked with TRIM37 in more than 16 cancer types. Because this analysis shows association rather than direction, both TRIM37-to-partner and partner-to-TRIM37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aggresome assembly grouped by TRIM37-low versus TRIM37-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM37→partner) and Y-score (partner→TRIM37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Aggresome assembly →	+0.196	+0.862	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Negative regulation of beige fat cell differentiation →	+0.141	+0.912	<.001	<.001	3	17
LUNG_SCLC	Negative regulation of centriole replication →	+0.164	+0.592	<.001	<.001	3	15
LUNG_SCLC	Inclusion body assembly →	+0.221	+0.705	<.001	.001	3	15
BLOOD_Myeloma	Regulation of centrosome cycle →	+0.082	+0.882	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.072	+0.637	<.001	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,264 associations by consensus.

Aggresome assembly by TRIM37 expression — SOFT_TISSUE

Explore this box plot interactively →