TRIM37

Across TCGA cell cohorts, TRIM37 mutation is significantly associated with the RNA expression of many other genes, with 142 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRIM37-associated genes across cancer lineages are OR56A3, SMIM33, and TMEM247. Each is linked with TRIM37 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM37-to-partner and partner-to-TRIM37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56A3 grouped by TRIM37-low versus TRIM37-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM37→partner) and Y-score (partner→TRIM37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR56A3 →	+0.638	+4.938	<.001	<.001	3	2
LARGE_INTESTINE	SMIM33 →	+0.528	+2.577	<.001	.007	3	2
STOMACH	TMEM247 →	+0.208	+3.247	.004	.003	3	2
UPPER_AERODIGESTIVE_TRACT	C4orf50 →	+0.013	+4.736	<.001	.009	3	2
OVARY	TSPY8 →	+0.031	+5.196	<.001	.005	3	1
BLOOD_Lymphoma	CABP5 →	+0.011	+4.452	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 142 associations by consensus.

OR56A3 by TRIM37 expression — BLOOD_Lymphoma

Explore this box plot interactively →