TRIM36

Across TCGA patient cohorts, TRIM36 mutation is significantly associated with the RNA expression of many other genes, with 4,077 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM36-associated genes across cancer lineages are NEK4P1, DYNC1H1, and CIDECP1. Each is linked with TRIM36 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRIM36-to-partner and partner-to-TRIM36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NEK4P1 grouped by TRIM36-low versus TRIM36-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM36→partner) and Y-score (partner→TRIM36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NEK4P1 →	+0.575	+3.795	<.001	.005	3	3
SKCM	DYNC1H1 →	+0.453	+2.031	.002	.005	3	3
UCEC	CIDECP1 →	+0.497	+2.638	<.001	<.001	3	3
LUSC	RN7SKP72 →	+0.185	+1.946	<.001	.008	3	2
HNSC	RNA5SP451 →	+0.190	+4.468	<.001	.006	3	2
STAD	OR4A49P →	+0.222	+3.804	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,077 associations by consensus.

NEK4P1 by TRIM36 expression — HNSC

Explore this box plot interactively →