TRIM36

Across TCGA cell cohorts, TRIM36 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,790 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TRIM36-associated GO terms across cancer lineages are Centrosome cycle, Regulation of microtubule-based process, and Mitotic sister chromatid segregation. Each is linked with TRIM36 in more than 10 cancer types. Because this analysis shows association rather than direction, both TRIM36-to-partner and partner-to-TRIM36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centrosome cycle grouped by TRIM36-low versus TRIM36-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM36→partner) and Y-score (partner→TRIM36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Centrosome cycle →	+0.072	+1.061	<.001	.002	3	11
LUNG_SCLC	Regulation of microtubule-based process →	+0.079	+1.766	<.001	<.001	3	10
BLOOD_Lymphoma	Mitotic sister chromatid segregation →	+0.062	+0.846	<.001	.002	3	10
SKIN	Microtubule cytoskeleton organization involved in mitosis →	+0.089	+0.928	.001	.003	3	9
URINARY_TRACT	Protein-DNA complex organization →	+0.055	+0.997	<.001	<.001	3	9
BONE	Microtubule organizing center organization →	+0.064	+1.344	.009	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,790 associations by consensus.

Centrosome cycle by TRIM36 expression — BLOOD_Leukemia

Explore this box plot interactively →