TRIM36

Across TCGA cell cohorts, TRIM36 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TRIM36-associated genes across cancer lineages are C4orf17, LYZL6, and SLC35G3. Each is linked with TRIM36 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM36-to-partner and partner-to-TRIM36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C4orf17 grouped by TRIM36-low versus TRIM36-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM36→partner) and Y-score (partner→TRIM36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	C4orf17 →	+0.011	+4.714	<.001	.002	3	1
BLOOD_Lymphoma	LYZL6 →	+0.077	+4.643	<.001	.005	3	1
LARGE_INTESTINE	SLC35G3 →	+0.011	+4.467	<.001	.004	3	1
LARGE_INTESTINE	DEFA4 →	+0.040	+5.022	<.001	.002	3	1
LARGE_INTESTINE	TMCO5A →	+0.019	+4.415	<.001	.007	3	1
LARGE_INTESTINE	TBC1D21 →	+0.015	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

C4orf17 by TRIM36 expression — BLOOD_Lymphoma

Explore this box plot interactively →