TRIM29

Across TCGA cell cohorts, TRIM29 mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRIM29-associated genes across cancer lineages are ANKRD30BL, FAM205A, and C18orf63. Each is linked with TRIM29 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM29-to-partner and partner-to-TRIM29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD30BL grouped by TRIM29-low versus TRIM29-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM29→partner) and Y-score (partner→TRIM29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ANKRD30BL →	+0.038	+4.734	.001	.002	3	2
LARGE_INTESTINE	FAM205A →	+0.014	+2.444	.003	.008	3	2
LUNG_SCLC	C18orf63 →	+0.009	+4.169	<.001	.001	3	2
SKIN	OOSP4A →	+0.130	+4.196	<.001	.002	3	2
LUNG_NSCLC_LUAD	OR56A4 →	+0.190	+4.947	<.001	.001	3	1
LUNG_NSCLC_LUAD	OR11A1 →	+0.041	+4.734	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

ANKRD30BL by TRIM29 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →