TRIM28

Across TCGA patient cohorts, TRIM28 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,550 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRIM28-associated proteins across cancer lineages are PRMT1, TRIM24, and SRSF9. Each is linked with TRIM28 in more than 7 cancer types. Because this analysis shows association rather than direction, both TRIM28-to-partner and partner-to-TRIM28 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM28 versus PRMT1 in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM28→partner) and Y-score (partner→TRIM28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PRMT1 →	+0.355	+0.656	<.001	<.001	3	8
GBM	TRIM24 →	+0.482	+0.535	<.001	<.001	3	7
GBM	SRSF9 →	+0.463	+0.549	<.001	<.001	3	7
LSCC	MRTO4 →	+0.452	+0.659	<.001	<.001	3	7
OV	UBE2M →	+0.333	+1.091	<.001	.001	3	7
LUAD	UTP4 →	+0.327	+0.640	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,550 associations by consensus.

TRIM28 vs PRMT1 — BRCA

Explore this scatter interactively →