Across TCGA patient cohorts, TRIM27 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,424 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRIM27-associated proteins across cancer lineages are GNL1, CMTR1, and DHX16. Each is linked with TRIM27 in more than 6 cancer types. Because this analysis shows association rather than direction, both TRIM27-to-partner and partner-to-TRIM27 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM27→partner) and Y-score (partner→TRIM27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GNL1 →	+0.274	+0.475	<.001	<.001	3	7
LSCC	CMTR1 →	+0.350	+0.437	<.001	<.001	3	6
OV	DHX16 →	+0.256	+0.531	.003	.005	2	7
LSCC	WRNIP1 →	+0.318	+0.369	<.001	<.001	3	6
LSCC	ZKSCAN8_S193 →	+0.881	+0.697	<.001	<.001	3	6
OV	BRD2 →	+0.259	+0.718	.001	<.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,424 associations by consensus.

Exploration

TRIM27 survival (RNA) · tumor vs normal (RNA) · all TRIM27 data types