TRIM25

Across TCGA patient cohorts, TRIM25 protein abundance is significantly associated with the RNA expression of many other genes, with 13,409 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TRIM25-associated genes across cancer lineages are NMI, OAS2, and IFI6. Each is linked with TRIM25 in more than 6 cancer types. Because this analysis shows association rather than direction, both TRIM25-to-partner and partner-to-TRIM25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM25 versus NMI in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM25→partner) and Y-score (partner→TRIM25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NMI →	+0.816	+0.187	<.001	<.001	3	7
LSCC	OAS2 →	+1.270	+0.291	<.001	<.001	3	7
UCEC	IFI6 →	+1.567	+0.200	<.001	<.001	3	7
HNSC	RTP4 →	+1.090	+0.143	<.001	<.001	3	7
HNSC	MX1 →	+1.380	+0.232	<.001	<.001	3	7
UCEC	IFI27 →	+1.627	+0.219	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,409 associations by consensus.

TRIM25 vs NMI — HNSC

Explore this scatter interactively →