TRIM2

Across TCGA patient cohorts, TRIM2 protein abundance is significantly associated with the RNA expression of many other genes, with 18,514 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TRIM2-associated genes across cancer lineages are SH3RF1, KLHL23, and ANXA2P1. Each is linked with TRIM2 in more than 6 cancer types. Because this analysis shows association rather than direction, both TRIM2-to-partner and partner-to-TRIM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM2 versus SH3RF1 in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM2→partner) and Y-score (partner→TRIM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SH3RF1 →	+0.794	+0.388	.003	.001	3	7
HNSC	KLHL23 →	+1.046	+0.645	<.001	<.001	3	7
LUAD	ANXA2P1 →	+1.118	+0.739	<.001	<.001	3	7
OV	PPFIBP2 →	+0.772	+0.441	<.001	<.001	3	6
UCEC	NWD1 →	+0.986	+0.439	<.001	<.001	3	6
OV	OPHN1 →	+0.803	+0.458	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,514 associations by consensus.

TRIM2 vs SH3RF1 — OV

Explore this scatter interactively →