TRIM14

Across TCGA patient cohorts, TRIM14 protein abundance is significantly associated with the RNA expression of many other genes, with 10,343 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRIM14-associated genes across cancer lineages are PARP9, UBE2L6, and IFI35. Each is linked with TRIM14 in more than 8 cancer types. Because this analysis shows association rather than direction, both TRIM14-to-partner and partner-to-TRIM14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM14 versus PARP9 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM14→partner) and Y-score (partner→TRIM14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PARP9 →	+0.922	+0.495	<.001	<.001	3	9
UCEC	UBE2L6 →	+1.016	+0.447	<.001	<.001	3	9
HNSC	IFI35 →	+1.037	+0.252	<.001	<.001	3	9
OV	SLC15A3 →	+0.863	+0.354	.001	.004	3	8
BRCA	TAP1 →	+1.005	+0.251	<.001	<.001	3	8
HNSC	PARP14 →	+1.426	+0.634	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,343 associations by consensus.

TRIM14 vs PARP9 — OV

Explore this scatter interactively →