TRIL

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TRIL RNA expression is significantly associated with the go_rna of many other GO terms, with 3,461 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TRIL-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with TRIL in more than 10 cancer types. Because this analysis shows association rather than direction, both TRIL-to-partner and partner-to-TRIL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by TRIL-low versus TRIL-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIL→partner) and Y-score (partner→TRIL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHNegative regulation of myoblast fusion →+0.133+0.259.001.002311
STOMACHNegative regulation of syncytium formation by plasma membrane fusion →+0.129+0.239.001.004310
STOMACHRegulation of syncytium formation by plasma membrane fusion →+0.116+0.229.001.006211
SOFT_TISSUEVesicle budding from membrane →+0.089+1.497<.001<.001310
LUNG_SCLCVesicle coating →+0.091+0.941.003.00539
STOMACHRegulation of myoblast fusion →+0.123+0.230.001.00639
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,461 associations by consensus.

Negative regulation of myoblast fusion by TRIL expression — STOMACH

Box plot of Negative regulation of myoblast fusion in TRIL-low vs TRIL-high samples in STOMACH.

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Exploration