TRIB3

Across TCGA patient cohorts, TRIB3 RNA expression is significantly associated with the RNA expression of many other genes, with 14,286 significant associations in total. ACC shows the largest number of these associations.

The most reproducible TRIB3-associated genes across cancer lineages are SHMT2, CARS1, and MARS1. Each is linked with TRIB3 in more than 30 cancer types. Because this analysis shows association rather than direction, both TRIB3-to-partner and partner-to-TRIB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIB3 versus SHMT2 in KICH, with a Pearson correlation of 0.76.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIB3→partner) and Y-score (partner→TRIB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KICH	SHMT2 →	+1.081	+2.008	<.001	<.001	3	31
ACC	CARS1 →	+0.924	+1.944	<.001	<.001	3	30
ACC	MARS1 →	+0.826	+1.355	<.001	<.001	3	30
ACC	LONP1 →	+0.690	+1.195	<.001	<.001	3	30
READ	NOP56 →	+0.955	+1.153	<.001	<.001	3	29
KICH	MTHFD2 →	+1.407	+2.174	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,286 associations by consensus.

TRIB3 vs SHMT2 — KICH

Explore this scatter interactively →