TRIB2

Across TCGA patient cohorts, TRIB2 protein abundance is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRIB2-associated genes across cancer lineages are REXO4, ZNF554, and NR2C2AP. Each is linked with TRIB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIB2-to-partner and partner-to-TRIB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIB2 versus REXO4 in GBM, with a Pearson correlation of -0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIB2→partner) and Y-score (partner→TRIB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	REXO4 →	-0.543	-0.629	<.001	.007	3	1
GBM	ZNF554 →	-0.440	-0.560	.009	.008	3	1
GBM	NR2C2AP →	-0.753	-0.630	.003	.007	3	1
GBM	GGNBP1 →	+0.179	+0.448	<.001	.006	3	1
GBM	TRAV8-6 →	+0.506	+0.496	.004	.002	3	1
GBM	LINC01679 →	+0.875	+0.533	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

TRIB2 vs REXO4 — GBM

Explore this scatter interactively →