TRIB2

Across TCGA patient cohorts, TRIB2 mutation is significantly associated with the RNA expression of many other genes, with 4,686 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIB2-associated genes across cancer lineages are DPP3P2, THAP3, and LINC01908. Each is linked with TRIB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRIB2-to-partner and partner-to-TRIB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DPP3P2 grouped by TRIB2-low versus TRIB2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIB2→partner) and Y-score (partner→TRIB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DPP3P2 →	+0.122	+2.578	.002	.006	3	3
UCEC	THAP3 →	+0.261	+1.797	.001	.007	3	3
SARC	LINC01908 →	+0.109	+5.111	<.001	.008	3	2
LUAD	MAGEB6 →	+0.399	+3.027	<.001	.009	3	2
COAD	MIR298 →	+0.256	+3.212	.005	.007	3	2
COAD	EIF4A1P3 →	+0.194	+2.823	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,686 associations by consensus.

DPP3P2 by TRIB2 expression — COAD

Explore this box plot interactively →