TRIB2

Across TCGA cell cohorts, TRIB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,774 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIB2-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Negative regulation of myoblast fusion, and Negative regulation of ubiquitin-dependent protein catabolic process. Each is linked with TRIB2 in more than 7 cancer types. Because this analysis shows association rather than direction, both TRIB2-to-partner and partner-to-TRIB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by TRIB2-low versus TRIB2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIB2→partner) and Y-score (partner→TRIB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.077	+3.105	.004	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.125	+1.393	<.001	.007	3	7
URINARY_TRACT	Negative regulation of ubiquitin-dependent protein catabolic process →	+0.073	+2.238	<.001	<.001	3	7
LARGE_INTESTINE	Regulation of intrinsic apoptotic signaling pathway →	+0.060	+1.960	.001	<.001	3	7
LARGE_INTESTINE	Regulation of synaptic transmission, GABAergic →	-0.124	-1.353	<.001	<.001	3	7
URINARY_TRACT	Negative regulation of protein catabolic process →	+0.080	+2.821	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,774 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by TRIB2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →