TRIB1

Across TCGA cell cohorts, TRIB1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TRIB1-associated genes across cancer lineages are OR10G2, OR6F1, and TMIGD1. Each is linked with TRIB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIB1-to-partner and partner-to-TRIB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10G2 grouped by TRIB1-low versus TRIB1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIB1→partner) and Y-score (partner→TRIB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR10G2 →	+0.050	+4.562	<.001	<.001	3	1
BREAST	OR6F1 →	+0.095	+4.421	<.001	.004	3	1
BREAST	TMIGD1 →	+0.023	+4.672	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR10G2 by TRIB1 expression — LARGE_INTESTINE

Explore this box plot interactively →