TRHDE

Across TCGA patient cohorts, TRHDE RNA expression is significantly associated with the protein abundance of many other proteins, with 20,053 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRHDE-associated proteins across cancer lineages are DCTN1, HYI, and MTR. Each is linked with TRHDE in more than 5 cancer types. Because this analysis shows association rather than direction, both TRHDE-to-partner and partner-to-TRHDE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRHDE versus DCTN1 in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRHDE→partner) and Y-score (partner→TRHDE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DCTN1 →	+0.252	+0.584	<.001	<.001	3	6
BRCA	HYI →	+0.400	+0.270	<.001	<.001	3	6
PDAC	MTR →	+0.279	+0.873	<.001	.001	3	6
UCEC	ARHGAP31 →	+0.428	+1.087	<.001	<.001	3	6
CCRCC	PLVAP →	+0.469	+1.016	<.001	<.001	3	5
UCEC	ARHGEF17 →	+0.456	+0.635	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,053 associations by consensus.

TRHDE vs DCTN1 — GBM

Explore this scatter interactively →