TRHDE

Across TCGA patient cohorts, TRHDE protein abundance is significantly associated with the RNA expression of many other genes, with 2,044 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRHDE-associated genes across cancer lineages are FCGR3B, FPR2, and AQP9. Each is linked with TRHDE in more than 2 cancer types. Because this analysis shows association rather than direction, both TRHDE-to-partner and partner-to-TRHDE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRHDE versus FCGR3B in HNSC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRHDE→partner) and Y-score (partner→TRHDE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FCGR3B →	+1.828	+1.884	<.001	<.001	3	3
HNSC	FPR2 →	+1.248	+1.568	.002	<.001	3	3
HNSC	AQP9 →	+1.273	+1.396	<.001	.001	3	2
GBM	S100A8 →	+1.206	+0.501	.001	.004	3	2
HNSC	CXCR1 →	+0.788	+0.846	.005	.004	3	2
CCRCC	PPBP →	+1.221	+0.629	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,044 associations by consensus.

TRHDE vs FCGR3B — HNSC

Explore this scatter interactively →