TRHDE

Across TCGA cell cohorts, TRHDE RNA expression is significantly associated with the go_rna of many other GO terms, with 2,711 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TRHDE-associated GO terms across cancer lineages are Regulation of fibroblast proliferation, Regulation of syncytium formation by plasma membrane fusion, and Integrin-mediated signaling pathway. Each is linked with TRHDE in more than 8 cancer types. Because this analysis shows association rather than direction, both TRHDE-to-partner and partner-to-TRHDE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of fibroblast proliferation grouped by TRHDE-low versus TRHDE-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRHDE→partner) and Y-score (partner→TRHDE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of fibroblast proliferation →	+0.094	+0.405	.002	.007	2	9
BONE	Regulation of syncytium formation by plasma membrane fusion →	+0.084	+1.831	.006	.003	3	8
KIDNEY	Integrin-mediated signaling pathway →	+0.148	+1.846	.008	<.001	3	7
KIDNEY	Regulation of cell-matrix adhesion →	+0.104	+1.606	.001	.004	3	7
BREAST	Urokinase plasminogen activator signaling pathway →	+0.827	+0.512	.006	.005	3	7
SOFT_TISSUE	Wound healing →	+0.083	+1.496	.001	<.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,711 associations by consensus.

Regulation of fibroblast proliferation by TRHDE expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →