TRHDE-AS1

Across TCGA pan-cancer cohorts, TRHDE-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TRHDE-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TRHDE-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types TRHDE-AS1 is over-expressed in tumor, although a few such as KIRC and LUAD show the opposite, repressed pattern.

KIRC, LUAD, and THCA are the cancer types where TRHDE-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRHDE-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−0.579	<.001	11	view →
LUAD	Female	II,III,IV	−0.422	<.001	9	view →
THCA	Female	II,III,IV	−0.132	<.001	9	view →
BRCA	All	All	−2.266	<.001	8	view →
LUSC	All	All	−0.272	.001	6	view →
READ	All	All	−0.208	.002	3	view →
COAD	Female	All	−0.114	<.001	3	view →
KIRP	All	III,IV	−0.868	.017	2	view →
UCEC	All	All	−0.541	<.001	2	view →
PRAD	All	All	−0.428	<.001	2	view →
HNSC	Male	IV	−0.147	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TRHDE-AS1–KIRC

Open the KIRC breakdown →