Across TCGA patient cohorts, TRGVB RNA expression is significantly associated with the go_rna of many other GO terms, with 6,418 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TRGVB-associated GO terms across cancer lineages are Alpha-beta T cell proliferation, Positive regulation of alpha-beta T cell proliferation, and Response to interleukin-2. Each is linked with TRGVB in more than 15 cancer types. Because this analysis shows association rather than direction, both TRGVB-to-partner and partner-to-TRGVB results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRGVB→partner) and Y-score (partner→TRGVB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Alpha-beta T cell proliferation →	+0.067	+0.042	<.001	<.001	3	16
SKCM	Positive regulation of alpha-beta T cell proliferation →	+0.084	+0.038	<.001	<.001	3	16
SKCM	Response to interleukin-2 →	+0.069	+0.030	<.001	<.001	3	16
SKCM	Positive regulation of T cell proliferation →	+0.062	+0.041	<.001	<.001	3	16
ESCA	T cell receptor signaling pathway →	+0.065	+0.057	<.001	<.001	2	16
STAD	T cell mediated immunity →	+0.047	+0.082	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,418 associations by consensus.

Exploration

TRGVB survival (RNA) · tumor vs normal (RNA) · all TRGVB data types