Across TCGA patient cohorts, TRGVA RNA expression is significantly associated with the go_rna of many other GO terms, with 6,767 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible TRGVA-associated GO terms across cancer lineages are Phagocytosis, Canonical NF-kappaB signal transduction, and Negative regulation of immune response. Each is linked with TRGVA in more than 26 cancer types. Because this analysis shows association rather than direction, both TRGVA-to-partner and partner-to-TRGVA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRGVA→partner) and Y-score (partner→TRGVA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Phagocytosis →	+0.045	+0.109	<.001	<.001	3	27
STAD	Canonical NF-kappaB signal transduction →	+0.044	+0.104	<.001	<.001	3	27
STAD	Negative regulation of immune response →	+0.042	+0.104	<.001	<.001	3	26
STAD	Negative regulation of cell activation →	+0.043	+0.136	<.001	<.001	3	26
STAD	Activation of innate immune response →	+0.042	+0.115	<.001	<.001	3	26
STAD	Regulation of leukocyte proliferation →	+0.046	+0.105	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,767 associations by consensus.

Exploration

TRGVA survival (RNA) · tumor vs normal (RNA) · all TRGVA data types