Across TCGA patient cohorts, TRGV11 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRGV11-associated genes across cancer lineages are RNU6-1026P, MIR550A1, and RNU6ATAC3P. Each is linked with TRGV11 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRGV11-to-partner and partner-to-TRGV11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRGV11→partner) and Y-score (partner→TRGV11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1026P →	+0.544	+4.937	<.001	.005	3	1
UCEC	MIR550A1 →	+0.607	+5.184	.002	.001	3	1
UCEC	RNU6ATAC3P →	+0.602	+4.809	<.001	.003	3	1
UCEC	IGHD1-26 →	+1.391	+4.484	<.001	.009	3	1
UCEC	RNA5SP36 →	+0.283	+4.551	.009	.009	3	1
UCEC	UBTFL7 →	+0.375	+4.398	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

TRGV11 survival (RNA) · tumor vs normal (RNA) · all TRGV11 data types