Across TCGA patient cohorts, TRGV10 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRGV10-associated genes across cancer lineages are RNU6-1301P, RNU1-124P, and RNU4-53P. Each is linked with TRGV10 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRGV10-to-partner and partner-to-TRGV10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRGV10→partner) and Y-score (partner→TRGV10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1301P →	+0.673	+4.078	.004	.005	3	1
UCEC	RNU1-124P →	+0.651	+4.061	.003	.005	3	1
UCEC	RNU4-53P →	+0.923	+3.800	<.001	.009	3	1
UCEC	NLGN4Y-AS1 →	+0.129	+4.352	<.001	.008	3	1
UCEC	KCND3-IT1 →	+0.176	+4.442	<.001	.007	3	1
UCEC	SNX18P7 →	+0.429	+3.976	.006	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

TRGV10 survival (RNA) · tumor vs normal (RNA) · all TRGV10 data types