Across TCGA pan-cancer cohorts, TREML5P Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TREML5P data layer compared with 20 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher TREML5P Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TREML5P expression acts as an unfavorable survival marker.

SKCM, LUSC, and UCEC are the cancer types where TREML5P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Median	II,III,IV	0.163	0.692	<.001	27	view →
LUSC	OS	Median	All	0.181	0.762	.005	18	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: TREML5P tumor-vs-normal RNA expression · all TREML5P data types