Across TCGA pan-cancer cohorts, TREML5P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of TREML5P’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where TREML5P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TREML5P is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

BLCA, LUSC, and KIRP are the cancer types where TREML5P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TREML5P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	+0.083	.012	6	view →
LUSC	All	All	−0.086	.002	4	view →
KIRP	Female	All	+0.071	.009	4	view →
LUAD	Male	II,III,IV	−0.104	.013	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: TREML5P RNA expression & survival · all TREML5P data types