TREM1

Across TCGA patient cohorts, TREM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,026 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TREM1-associated proteins across cancer lineages are ITGAM, PPP1R18_S224, and LOXL2. Each is linked with TREM1 in more than 9 cancer types. Because this analysis shows association rather than direction, both TREM1-to-partner and partner-to-TREM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TREM1 versus ITGAM in GBM, with a Pearson correlation of 0.81.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TREM1→partner) and Y-score (partner→TREM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ITGAM →	+0.890	+1.876	<.001	<.001	3	10
LSCC	PPP1R18_S224 →	+0.741	+1.058	<.001	<.001	3	9
PDAC	LOXL2 →	+0.932	+1.024	<.001	<.001	3	9
GBM	NCF2 →	+0.880	+1.870	<.001	<.001	3	9
GBM	HK3 →	+1.088	+1.824	<.001	<.001	3	9
GBM	UPP1 →	+0.710	+1.209	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,026 associations by consensus.

TREM1 vs ITGAM — GBM

Explore this scatter interactively →