Across TCGA patient cohorts, TRDV1 mutation is significantly associated with the RNA expression of many other genes, with 602 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRDV1-associated genes across cancer lineages are SNORA10B, HSD17B7P1, and RNA5SP486. Each is linked with TRDV1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRDV1-to-partner and partner-to-TRDV1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRDV1→partner) and Y-score (partner→TRDV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORA10B →	+0.515	+4.616	<.001	.001	3	2
UCEC	HSD17B7P1 →	+0.167	+4.393	<.001	.002	3	2
SKCM	RNA5SP486 →	+0.084	+5.009	<.001	.001	3	2
SKCM	RNA5SP444 →	+0.098	+3.353	<.001	.003	3	2
SKCM	RNA5SP302 →	+0.104	+4.369	<.001	<.001	3	2
SKCM	SAR1AP3 →	+0.034	+2.270	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 602 associations by consensus.

Exploration

TRDV1 survival (RNA) · tumor vs normal (RNA) · all TRDV1 data types