Across TCGA pan-cancer cohorts, TRDV1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated TRDV1 data layer compared with 1 for mutation status.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher TRDV1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TRDV1 expression acts as an unfavorable survival marker, although some lineages such as OV and CESC show a favorable association.

OV, CESC, and SKCM are the cancer types where TRDV1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Tertile	All	0.431	0.298	.003	108	view →
CESC	DFS	Tertile	All	0.827	0.632	<.001	100	view →
SKCM	OS	Tertile	All	0.439	0.278	<.001	93	view →
BRCA	DFS	Tertile	All	0.632	0.477	<.001	82	view →
HNSC	DFS	Median	All	0.772	0.648	<.001	54	view →
UCEC	DFS	Tertile	II,III,IV	0.760	0.278	.005	54	view →
LGG	OS	Tertile	All	0.797	0.910	<.001	39	view →
BLCA	DFS	Quartile	II,III,IV	0.690	0.557	.007	36	view →
LUAD	DFS	Median	All	0.717	0.613	.005	34	view →
LIHC	DFS	Median	All	0.405	0.197	<.001	28	view →
UVM	DFS	Tertile	II,III,IV	0.396	0.650	.029	22	view →
SARC	OS	Tertile	All	0.590	0.412	.002	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

Exploration

Same gene, other analysis: TRDV1 tumor-vs-normal RNA expression · all TRDV1 data types