Across TCGA patient cohorts, TRDN protein abundance is significantly associated with the RNA expression of many other genes, with 1,813 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TRDN-associated genes across cancer lineages are TMEM51-AS1, SEC14L2, and PLS3. Each is linked with TRDN in more than 1 cancer types. Because this analysis shows association rather than direction, both TRDN-to-partner and partner-to-TRDN results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRDN→partner) and Y-score (partner→TRDN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TMEM51-AS1 →	-0.456	-0.915	.003	.007	3	2
OV	SEC14L2 →	-0.597	-0.733	.006	.004	3	1
OV	PLS3 →	-1.223	-0.979	.003	.006	3	1
OV	MYH14 →	-1.610	-1.194	.008	.002	2	2
OV	CLEC11A →	-1.280	-1.099	.006	.001	3	1
OV	ERF →	-0.555	-0.793	.007	.002	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,813 associations by consensus.

Exploration

TRDN survival (RNA) · tumor vs normal (RNA) · all TRDN data types